Browsing by Contributors Angiolillo, Dominick J

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2018 Lancet Volume 392 Issue 10150 September (16).pdf.jpg2018BASKET-SMALL 2 : advancing DCB beyond in-stent restenosisAngiolillo, Dominick J
2017 JACC Volume 69 Issue 23 June (20).pdf.jpg2017Byron Cryer , MD Upendra Marathi , PhD Brigham and Women ’ s Hospital Heart and Vascular Center Harvard Medical School 75 Francis Street Boston , Massachusetts 02115 REPLY : Collapse of the Aspirin Empire Drs . Cerit and Duygu raise an interesting question of whether diabetic gastroparesis may play a role in apparent aspirin resistance ” in diabetic patients ( 1 ). It is possible that in some patients , diabetic gastroparesis impairs absorption of a number of enteric coated ( EC ) drugs , including EC aspirin . Indeed , the incidence of gastroparesis in patients with diabetes may be as high as 30 % to 40 % ( 2 ). Because blood glucose is important in regulating gastric emptying , as well as other factors , it is possible that patients treated with EC aspirin have variable gastric emptying and a higher frequency of prolonged tablet retention in the stomach ( 3 ). With a greater gastric residence time , the amount of aspirin available to be dissolved and absorbed in the upper gastrointestinal tract may be lower after EC aspirin than after In patients with diabetic gastroparesis , the lower rate and extent of aspirin absorption could conceivably be magni fi ed . It is also possible that patients with diabetic gastroparesis have more advanced diabetes , and are therefore more likely to have heightened platelet activity . This potential effect on platelets may then appear to manifest as aspirin resistance ” as well ( 4 ). However , our study did not explicitly evaluate the presence though or the absence of diabetic aspirin gastroparesis , formulations studied did not appear to have any issues with impaired absorption ( 5 ). As such , more work is certainly needed on de fi ning the optimal antiplatelet therapy in diabetic patients . Deepak L . Bhatt , MD , MPH Tilo Grosser , MD Jing fei Dong , MD , PhD Douglas Logan , MD Walter Jeske , PhDAngiolillo, Dominick J; Iii, Andrew L Frelinger; Liang, Juan
2012medicine article bd (49).pdf.jpg2012Cigarette Smoking Is Associated With a Dose-Response Effect in Clopidogrel-Treated Patients With Diabetes Mellitus and Coronary Artery DiseaseResults of a Pharmacodynamic StudyUeno, Masafumi; Ferreiro, José Luis; Desai, Bhaloo; Tomasello, Salvatore D; Tello-Montoliu, Antonio; Capodanno, Davide; Capranzano, Piera; Kodali, Murali; Dharmashankar, Kodlipet; Charlton, Ronald K; Bass, Theodore a; Angiolillo, Dominick J
2013medicine article ar (401).pdf.jpg2013Consensus and Update on the Definition of On-Treatment Platelet Reactivity to Adenosine Diphosphate Associated With Ischemia and BleedingPrice, Matthew J; Jeong, Young-hoon; Angiolillo, Dominick J; Stone, Gregg W; Curzen, Nick; Hons, B M; Geisler, Tobias; Berg, Jurrien; Kirtane, Ajay; Siller-matula, Jolanta; Mahla, Elisabeth; Becker, Richard C; Bhatt, Deepak L; Waksman, Ron; Rao, Sunil V; Alexopoulos, Dimitrios; Marcucci, Rossella; Reny, Jean-luc; Trenk, Dietmar; Sibbing, Dirk; Gurbel, Paul A; Group, Working
2018 CIRCULATION 137 Issue 1 January (1).pdf.jpg2018Editor-in-Chief Joseph A. HillHill, Joseph A; Lemos, James A De; Mcguire, Darren K; Mauri, Laura; Al-khatib, Sana M; Beckman, Joshua A; Berry, Jarett D; Chin, Kelly; Das, Sandeep R; Delgado, Victoria; Diercks, Deborah B; Drazner, Mark H; Eschenhagen, Thomas; Ezekowitz, Justin; Gardner, Timothy J; Goto, Shinya; Greil, Gerald; Hundley, W Gregory; Hankey, Graeme J; James, Stefan; Kumbhani, Dharam; Lavandero, Sergio; Link, Mark S; Lowenstein, Charles J; Ma, Chang-sheng; Mayosi, Bongani M; Town, Cape; Ping, Peipei; Angeles, Los; Post, Wendy S; Rohatgi, Anand; Sadek, Hesham A; Sattar, Naveed A; Steg, Philippe Gabriel; Sweitzer, Nancy K; Vongpatanasin, Wanpen; Watson, Karol E; Angeles, Los; Bittner, Vera; Hobbs, Helen H; Olson, Eric N; Willerson, James T; Neeland, Ian J; Hampton, Tracy; Rutherford, John D; Ayers, Colby; Albert, Michelle A; Albert, Christine M; Alexander, John H; Alexander, Karen P; Anderson, Cheryl A M; Anderson, Mark E; Angiolillo, Dominick J; Antman, Elliott M; Armstrong, Paul W; Aronow, Herbert D; Merz, C Noel Bairey; Bax, Jeroen J; Benjamin, Emelia J; Benjamin, Ivor J; Berger, Jeffrey S; Bethel, M Angelyn; Bittner, Vera; Blumenthal, Roger S; Bonaca, Marc P; Byrne, Robert; Camici, Paolo G; Crea, Filippo; Creager, Mark A; Criqui, Michael H; Curtis, Anne B; Curtis, Jeptha P; Cushman, Mary; Eaton, Philip; Ellenbogen, Kenneth A; Erlinge, David; Frey, Norbert; Garry, Daniel J; Gatzoulis, Michael A; Marx, Nikolaus
2017 JACC Volume 69 Issue 6 February (4).pdf.jpg2017Enteric Coating and Aspirin Nonresponsiveness in Patients With Type 2 Diabetes MellitusBhatt, Deepak L; Grosser, Tilo; Dong, Jing-fei; Logan, Douglas; Jeske, Walter; Angiolillo, Dominick J; Lei, Lanyu; Liang, Juan; Moore, Jason E; Cryer, Byron; Marathi, Upendra
2012medicine article bi (137).pdf.jpg2012The Evolution of Antiplatelet Therapy in the Treatment of Acute Coronary Syndromes From Aspirin to the Present DayAngiolillo, Dominick J
2017 LANCET Volume 390 Issue 10104 October (9).pdf.jpg2017A hopeful therapy for Niemann-Pick C diseasesAngiolillo, Dominick J
2015 JACC Volume 8 Issue 11 September (11).pdf.jpg2015Impact of Escalating Loading DoseFranchi, Francesco; Rollini, Fabiana; Cho, Jung Rae; Bhatti, Mona; Degroat, Christopher; Ferrante, Elisabetta; Dunn, Elizabeth C; Nanavati, Amit; Carraway, Edward; Suryadevara, Siva; Zenni, Martin M; Guzman, Luis A; Bass, Theodore A; Angiolillo, Dominick J
2017 JACCCI Volume 10 Issue 13 July (21).pdf.jpg2017In Vitro Pharmacodynamic Effects of Cangrelor Receptor – Mediated Signaling in Ticagrelor Treated Patients Transradial Mini InvasiveRollini, Fabiana; Franchi, Francesco; Thano, Estela; Faz, Gabriel; Park, Yongwhi; Kureti, Megha; Cho, Jung Rae; Aas, Latonya Been; Bass, Theodore A; Angiolillo, Dominick J
2013medicine article ar (84).pdf.jpg2013The Influence of Smoking Status on the Pharmacokinetics and Pharmacodynamics of Clopidogrel and Prasugrel The PARADOX StudyGurbel, Paul A; Bliden, Kevin P; Logan, Douglas K; Kereiakes, Dean J; Lasseter, Kenneth C; White, Alex; Angiolillo, Dominick J; Jakubowski, Joseph A; Ojeh, Clement K; Jeong, Young-hoon; Tantry, Udaya S; Baker, Brian A; Harm, P D
2017 JACCCI Volume 10 Issue  5 March (20).pdf.jpg2017Inside This IssueCapodanno, Davide; Angiolillo, Dominick J
2013medicine article ar (461).pdf.jpg2013Inside This IssueTantry, Udaya S; Bonello, Laurent; Aradi, Daniel; Price, Matthew J; Jeong, Young-hoon; Angiolillo, Dominick J; Stone, Gregg W; Curzen, Nick; Geisler, Tobias; Kirtane, Ajay; Siller-matula, Jolanta; Mahla, Elisabeth; Becker, Richard C; Bhatt, Deepak L; Waksman, Ron; Rao, Sunil V; Alexopoulos, Dimitrios; Marcucci, Rossella; Reny, Jean-luc; Trenk, Dietmar; Sibbing, Dirk; Gurbel, Paul A; Chan, Paul S; Rao, Sunil V; Bhatt, Deepak L; Rumsfeld, John S; Gurm, Hitinder S; Nallamothu, Brahmajee K; Cavender, Matthew A; Kennedy, Kevin F; Spertus, John A
2018 JCI Volume 11 Issue 5 March (9).pdf.jpg2018Inside This IssueRossini, Roberta; Tarantini, Giuseppe; Musumeci, Giuseppe; Masiero, Giulia; Barbato, Emanuele; Calabrò, Paolo; Capodanno, Davide; Leonardi, Sergio; Lettino, Maddalena; Limbruno, Ugo; Menozzi, Alberto; Marchese, U O Alfredo; Saia, Francesco; Valgimigli, Marco; Ageno, Walter; Falanga, Anna; Corcione, Antonio; Locatelli, Alessandro; Montorsi, Marco; Piazza, Diego; Stella, Andrea; Bozzani, Antonio; Parolari, Alessandro; Carone, Roberto; Angiolillo, Dominick J
2017 JACC Volume 69 Issue 6 February (2).pdf.jpg2017More Time to SORT OUT Clinical Outcomes After First Generation Drug Eluting Stents: Related Versus Unrelated Events David J. Moliterno, Khaled M. Ziada 625Bhatt, Deepak L; Grosser, Tilo; Dong, Jing-fei; Logan, Douglas; Jeske, Walter; Angiolillo, Dominick J; Iii, Andrew L Frelinger; Lei, Lanyu; Liang, Juan; Moore, Jason E; Cryer, Byron; Marathi, Upendra; Patrono, Carlo; Rocca, Bianca; Hansen, Peter R; Christiansen, Evald H
2014medicine article ai (81).pdf.jpg2014Pharmacodynamic Effects of Cangrelor on Platelet P2Y 12 Receptor – Mediated Signaling in Prasugrel-Treated Patients Pharmacodynamic Effects of Cangrelor on Platelet P2Y 12 Receptor – Mediated Signaling in Prasugrel-Treated PatientsRollini, Fabiana; Franchi, Francesco; Tello-montoliu, Antonio; Patel, Ronakkumar; Darlington, Andrew; Ferreiro, José Luis; Cho, Jung Rae; Muñiz-lozano, Ana; Desai, Bhaloo; Zenni, Martin M; Guzman, Luis A; Bass, Theodore A; Angiolillo, Dominick J
2012medicine article bc (547).pdf.jpg2012Pharmacodynamic Effects of Prasugrel Dosing Regimens in Patients on Maintenance Prasugrel Therapy Results of a Prospective Randomized StudyTello-montoliu, Antonio; Tomasello, Salvatore D; Ferreiro, José Luis; Ueno, Masafumi; Seecheran, Naveen; Desai, Bhaloo; Kodali, Murali; Bass, Theodore A; Angiolillo, Dominick J
2016 Jacc Volume 9 Issue 11 June (23).pdf.jpg2016Pharmacodynamic Effects of SwitchingThano, Estela; Hu, Jenny; Kureti, Megha; Aggarwal, Niti; Durairaj, Ashwin; Been, Latonya; Zenni, Martin M; Guzman, Luis A; Suryadevara, Siva; Antoun, Patrick; Bass, Theodore A; Angiolillo, Dominick J
2015 JACC Volume 8 Issue 8 July (7).pdf.jpg2015Pharmacodynamic Effects of Ticagrelor Dosing Regimens in Patients on Maintenance Ticagrelor TherapyCho, Jung Rae; Rollini, Fabiana; Franchi, Francesco; Degroat, Christopher; Bhatti, Mona; Dunn, Elizabeth C; Ferrante, Elisabetta; Muniz-lozano, Ana; Suryadevara, Siva; Zenni, Martin M; Guzman, Luis A; Bass, Theodore A; Angiolillo, Dominick J
2012medicine article bc (284).pdf.jpg2012Platelet Biology and Response to Antiplatelet Therapy in Women Implications for the Development and Use of Antiplatelet Pharmacotherapies for Cardiovascular DiseaseWang, Tracy Y; Angiolillo, Dominick J; Cushman, Mary; Sabatine, Marc S; Bray, Paul F; Smyth, Susan S; Dauerman, Harold L; French, Patricia A; Becker, Richard C