Browsing by Contributors Lu, Xiaoyun

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Showing results 1 to 16 of 16
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2019 JMC Volume 62 Issue 16 August (7).pdf.jpg20192-Amino-2,3-dihydro-1 H -indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer EfficacyZhu, Dongsheng; Huang, Huocong; Pinkas, Daniel M.; Luo, Jinfeng; Ganguly, Debolina; Fox, Alice E.; Arner, Emily; Xiang, Qiuping; Tu, Zheng-Chao; Bullock, Alex N.; Brekken, Rolf a.; Ding, Ke; Lu, Xiaoyun
2018 JMC Volume 61 Issue 17 September (39).pdf.jpg2018Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2- a]pyrazin-3-ylethynyl)-4-isopropyl- N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2Wang, Zhen; Zhang, Yali; Pinkas, Daniel M.; Fox, Alice E.; Luo, Jinfeng; Huang, Huocong; Cui, Shengyang; Xiang, Qiuping; Xu, Tingting; Xun, Qiuju; Zhu, Dongsheng; Tu, Zhengchao; Ren, Xiaomei; Brekken, Rolf a.; Bullock, Alex N.; Liang, Guang; Ding, Ke; Lu, Xiaoyun
2012medicine article a (226).pdf.jpg2012Design, Synthesis, and Biological Evaluation of Novel Conformationally Constrained Inhibitors Targeting Epidermal Growth Factor Receptor Threonine 790 → Methionine 790 MutantChang, Shaohua; Zhang, Lianwen; Xu, Shilin; Luo, Jinfeng; Lu, Xiaoyun; Zhang, Zhang; Xu, Tianfeng; Liu, Yingxue; Tu, Zhengchao; Xu, Yong; Ren, Xiaomei; Geng, Meiyu; Ding, Jian; Pei, Duanqing; Ding, Ke
2018 JoMC Volume 61 Issue 6 March (11).pdf.jpg2018Design, Synthesis, and Structure-Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5- d] pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase InhibitorsXun, Qiuju; Zhang, Zhang; Luo, Jinfeng; Tong, Linjiang; Huang, Minhao; Wang, Zhen; Zou, Jian; Liu, Yingqiang; Xu, Yong; Xie, Hua; Tu, Zheng Chao; Lu, Xiaoyun; Ding, Ke
2019 JournalofMedicalChemistry Volume 62 Issue 6 March (5).pdf.jpg2019Fibroblast Growth Factor Receptor 4 ( FGFR4 ) Selective Inhibitors as Hepatocellular Carcinoma Therapy : Advances and Prospects MiniperspectiveLu, Xiaoyun; Chen, Hao; Patterson, Adam V; Smaill, Je B; Ding, Ke
2012medicine article a (182).pdf.jpg2012Huimin Cheng, † , ⊥ Junting Wan, † Meng-I Lin, ‡ Yingxue Liu, † Xiaoyun Lu, † Jinsong Liu, † Yong Xu, † Jianxin Chen, § Zhengchao Tu, † Yih-Shyun E. Cheng, ‡ and Ke Ding * , † †Cheng, Huimin; Wan, Junting; Lin, Meng-i; Liu, Yingxue; Lu, Xiaoyun; Liu, Jinsong; Xu, Yong; Chen, Jianxin; Tu, Zhengchao; Cheng, Yih-shyun E; Ding, Ke
2014medicine article a (200).pdf.jpg2014Identi fi cation and Optimization of New Dual Inhibitors of B ‑ Raf and Epidermal Growth Factor Receptor Kinases for Overcoming Resistance against VemurafenibCheng, Huimin; Chang, Yu; Zhang, Lianwen; Luo, Jinfeng; Tu, Zhengchao; Lu, Xiaoyun; Zhang, Qingwen; Lu, Jibu; Ren, Xiaomei; Ding, Ke
2013medicine article a (72).pdf.jpg2013Identi fi cation of GZD824 as an Orally Bioavailable Inhibitor That Targets Phosphorylated and Nonphosphorylated Breakpoint Cluster Region − Abelson (Bcr-Abl) Kinase and Overcomes Clinically Acquired Mutation-Induced Resistance against ImatinibRen, Xiaomei; Pan, Xiaofen; Zhang, Zhang; Wang, Deping; Lu, Xiaoyun; Li, Yupeng; Wen, Donghai; Long, Huoyou; Luo, Jinfeng; Feng, Yubing; Zhuang, Xiaoxi; Zhang, Fengxiang; Liu, Jianqi; Leng, Fang; Lang, Xingfen; Bai, Yang; She, Miaoqin; Tu, Zhengchao; Pan, Jingxuan; Ding, Ke
2013medicine article a (272).pdf.jpg2013Mingshan Gao, † , ‡ , § Lei Duan, † , § Jinfeng Luo, † Lianwen Zhang, † Xiaoyun Lu, † Yan Zhang, † Zhang Zhang, † Zhengchao Tu, * , † Yong Xu, † Xiaomei Ren, † and Ke Ding * , † †Gao, Mingshan; Duan, Lei; Luo, Jinfeng; Zhang, Lianwen; Lu, Xiaoyun; Zhang, Yan; Zhang, Zhang; Tu, Zhengchao; Xu, Yong; Ren, Xiaomei; Ding, Ke
2014medicine article a (88).pdf.jpg2014Novel Anaplastic Lymphoma Kinase Inhibitors Targeting Clinically Acquired ResistanceLu, Xiaoyun; Ding, Ke
2013medicine article a (707).pdf.jpg2013Shilin Xu, † , § Tianfeng Xu, † , § Lianwen Zhang, † Zhang Zhang, † Jinfeng Luo, † Yingxue Liu, † Xiaoyun Lu, † Zhengchao Tu, † Xiaomei Ren, † and Ke Ding * , † †Xu, Shilin; Xu, Tianfeng; Zhang, Lianwen; Zhang, Zhang; Luo, Jinfeng; Liu, Yingxue; Lu, Xiaoyun; Tu, Zhengchao; Ren, Xiaomei; Ding, Ke
2015 JMC Volume 58 Issue Aril (2).pdf.jpg2015Small Molecule Discoidin Domain Receptor Kinase Inhibitors and Potential Medical ApplicationsLi, Yupeng; Lu, Xiaoyun; Ren, Xiaomei; Ding, Ke
2019 JoMC Volume 62 Issue 15 August (15).pdf.jpg2019Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFR L858R/T790M/C797S )Shen, Jiayi; Zhang, Tao; Zhu, Su-Jie; Sun, Min; Tong, Linjiang; Lai, Mengzhen; Zhang, Rong; Xu, Wei; Wu, Ruibo; Ding, Jian; Yun, Cai-Hong; Xie, Hua; Lu, Xiaoyun; Ding, Ke
2016 JMC Volume 59 Issue 12 June (10).pdf.jpg2016Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) InhibitorsMo, Cheng; Zhou, Yang; Xu, Yong; Tu, Zhengchao; Ren, Xiaomei; Lu, Xiaoyun; Brekken, Rolf A
2017 JMC Volume 60 Issue 13 July (41).pdf.jpg2017Yu ChangChang, Yu; Lu, Xiaoyun; Shibu, Marthandam Asokan; Dai, Yi-bo; Luo, Jinfeng; Zhang, Yan; Li, Yingjun; Zhao, Peng; Zhang, Zhang; Xu, Yong; Tu, Zheng-chao; Zhang, Qing-wen; Yun, Cai-hong; Huang, Chih-yang; Ding, Ke
2012medicine article a (737).pdf.jpg2012Yupeng Li, † , ‡ , § Mengjie Shen, † , ‡ , § Zhang Zhang, † Jinfeng Luo, † Xiaofen Pan, † Xiaoyun Lu, † Huoyou Long, † Donghai Wen, † Fengxiang Zhang, † Fang Leng, † Yingjun Li, † , ‡ Zhengchao Tu, † Xiaomei Ren, † and Ke Ding * , † †Li, Yupeng; Shen, Mengjie; Zhang, Zhang; Luo, Jinfeng; Pan, Xiaofen; Lu, Xiaoyun; Long, Huoyou; Wen, Donghai; Zhang, Fengxiang; Leng, Fang; Li, Yingjun; Tu, Zhengchao; Ren, Xiaomei; Ding, Ke