جهت دسترسی به کاربرگه ی زیر، از این لینک استفاده کنید. http://dl.kums.ac.ir/handle/Hannan/128450
Title: Observation versus neck dissection for positron-emission tomography-negative lymphadenopathy after chemoradiotherapy
Authors: Khodayari, Behnood;Daly, Megan E.;Bobinski, Matthew;Farwell, D. Gregory;Shelton, David K.;Chen, Allen M.
Keywords: Chemoradiotherapy;Cancer;lymphadenopathy;observation;positron-emission tomography
Year: 2014
Abstract: OBJECTIVES/HYPOTHESIS: To analyze outcomes among patients with residual positron-emission tomography (PET)-negative lymphadenopathy after chemoradiotherapy for head and neck cancer based on whether or not they underwent neck dissection. STUDY DESIGN: Retrospective review. METHODS: Fifty-five patients with stage III/IV squamous cell carcinoma of the head and neck were identified with residual PET-negative lymphadenopathy based on standardized uptake value of <3. All patients had been treated with chemoradiotherapy to a median dose of 70 Gy (range, 60-4 Gy). RESULTS: With a median follow-up of 30 months (range, 6-67 months), the 3-year overall survival (85% vs. 81%, P = .57), progression-free survival (88% vs. 88%, P = .42), and local-regional control (96% vs. 100%, P = .68), did not differ between patients treated by neck dissection or observation. CONCLUSIONS: Omission of neck dissection appears to be reasonable for patients with residual lymphadenopathy but negative PET after chemoradiotherapy for head and neck cancer. LEVEL OF EVIDENCE: 4. Laryngoscope, 2013.
URI: http://dl.kums.ac.ir/handle/Hannan/128450
ISSN: 1531-4995 (Electronic)\r0023-852X (Linking)
volume: Volume 124
Issue: Issue 4
month: April
More Information: Volume : 124Issue : 4Start page : 902
END PAGES : 906
Appears in Collections:Laryngoscope

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