صفحه اصلی مجموعه  Journal of Medicinal Chemistry

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130.pdf.jpg24-Jun-2014The Discovery of Polo-Like Kinase 4 Inhibitors: Design and Optimization of Spiro[cyclopropane-1,3'[3H]indol]-2'(1'H)-ones as Orally Bioavailable Antitumor AgentsSampson, Peter B; Liu, Yong; Patel, Narendra Kumar; Feher, Miklos; Forrest, Bryan; Li, Sze-Wan; Edwards, Louise; Laufer, Radoslaw; Lang, Yunhui; Ban, Fuqiang; Awrey, Donald E; Mao, Guodong; Plotnikova, Olga; Leung, Genie; Hodgson, Richard; Mason, Jacqueline; Wei, Xin; Kiarash, Reza; Green, Erin; Qiu, Wei; Chirgadze, Nickolay Y; Mak, Tak W; Pan, Guohua; Pauls, Henry W
2014medicine article a (793).PDF.jpg2014Stephanie Federico, † Antonella Ciancetta, ‡ Davide Sabbadin, ‡ Silvia Paoletta, ‡ Giorgia Pastorin, § Barbara Cacciari, ⊥ Karl Norbert Klotz, □ Stefano Moro, * , ‡ and Giampiero Spalluto * , † † ‡Federico, Stephanie; Ciancetta, Antonella; Sabbadin, Davide; Paoletta, Silvia; Pastorin, Giorgia; Cacciari, Barbara; Klotz, Karl Norbert; Moro, Stefano; Spalluto, Giampiero; Chimiche, Scienze; Trieste, Universita; Europa, Piazzale; Trieste, I-
2012medicine article a (23).pdf.jpg2012Stilbene-chalcone hybrids: Design, synthesis, and evaluation as a new class of antimalarial scaffolds that trigger cell death through stage specific apoptosisSharma, Naina; Mohanakrishnan, Dinesh; Shard, Amit; Sharma, Abhishek; Saima; Sinha, Arun K.; Sahal, Dinkar
2015 JMC Volume 58 Issue 1 January (14).pdf.jpg2015Discovery of Selective and Orally Bioavailable Protein Kinase C θ (PKC θ ) Inhibitors from a Fragment HitGeorge, Dawn M; Breinlinger, Eric C; Friedman, Michael; Zhang, Yang; Wang, Jianfei; Argiriadi, Maria; Bansal-pakala, Pratima; Barth, Martine; Duignan, David B; Honore, Prisca; Lang, Qingyu; Mittelstadt, Scott; Potin, Dominique; Rundell, Lian; Edmunds, Jeremy J
2015 JMC Volume 58 Issue 1 January (13).pdf.jpg2015Development of First Lead Structures for Phosphoinositide 3 ‑ Kinase- C2 γ InhibitorsInhibitors, C; Freitag, Anne; Prajwal, Prajwal; Shymanets, Aliaksei; Harteneck, Christian; Nu, Bernd; Kubbutat, Michael; Totzke, Frank; Laufer, Stefan A
2015 JMC Volume 58 Issue 1 January (1).pdf.jpg2015Advancing the Kinase Field: New Targets and Second Generation Inhibitors-
2015 JMC Volume 58 Issue 1 January (11).pdf.jpg2015Discovery of Type II Inhibitors of TGF β -Activated Kinase 1 (TAK1) and Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2)Kinase, Mitogen-activated Protein; Kinase, Kinase; Tan, Li; Nomanbhoy, Tyzoon; Gurbani, Deepak; Patricelli, Matthew; Hunter, John; Geng, Jiefei; Herhaus, Lina; Zhang, Jianming; Pauls, Eduardo; Ham, Youngjin; Choi, Hwan Geun; Xie, Ting; Deng, Xianming; Buhrlage, Sara J
2015 JMC Volume 58 Issue 1 January (15).pdf.jpg2015Pascal Dao, † Nikaia Smith, † Ce l ́ ine Tomkiewicz-Raulet, ‡ Expe d ́ ite Yen-Pon, † Marta Camacho-Artacho, § Daniel Lietha, § Jean-Phillipe Herbeuval, † Xavier Coumoul, ‡ Christiane Garbay, † and Huixiong Chen * , † , ∥ †Camacho-artacho, Marta; Lietha, Daniel; Herbeuval, Jean-phillipe; Coumoul, Xavier; Garbay, Christiane; Chen, Huixiong
2015 JMC Volume 58 Issue 1 January (12).pdf.jpg2015Discovery of Novel 2,4-Diarylaminopyrimidine Analogues (DAAPalogues) Showing Potent Inhibitory Activities against Both Wild-type and Mutant ALK KinasesSong, Zilan; Yang, Yanhong; Liu, Zhiqing; Peng, Xia; Guo, Junfeng; Yang, Xinying; Wu, Kui; Ai, Jing; Ding, Jian; Geng, Meiyu; Zhang, Ao
2015 JMC Volume 58 Issue 1 January (10).pdf.jpg2015Optimization of Potent DFG-in Inhibitors of Platelet Derived Growth Factor Receptor β (PDGF-R β ) Guided by Water ThermodynamicsHorbert, Rebecca; Pinchuk, Boris; Johannes, Eugen; Schlosser, Joachim; Schmidt, Dorian; Cappel, Daniel; Totzke, Frank; Scha, Christoph; Peifer, Christian
2015 JMC Volume 58 Issue 1 January (5).pdf.jpg2015Inhibitors of c ‑ Jun N ‑ Terminal Kinases: An UpdateKoch, Pierre; Gehringer, Matthias; Laufer, Stefan A
2015 JMC Volume 58 Issue 1 January (22).pdf.jpg2015Optimized Protein Kinase C θ (PKC θ ) Inhibitors Reveal Only Modest Anti-in fl ammatory E ffi cacy in a Rodent Model of ArthritisGeorge, Dawn M; Breinlinger, Eric C; Argiriadi, Maria A; Zhang, Yang; Wang, Jianfei; Bansal-pakala, Pratima; Duignan, David B; Honore, Prisca; Lang, Qingyu; Mittelstadt, Scott; Rundell, Lian; Schwartz, Annette; Sun, Jiakang; Edmunds, Jeremy J
2015 JMC Volume 58 Issue 1 January (20).pdf.jpg2015Development of Organometallic S6K1 InhibitorsQin, Jie; Rajaratnam, Rajathees; Feng, Li; Salami, Jemilat; Barber-rotenberg, Julie S; Domsic, John; Reyes-uribe, Patricia; Liu, Haiying; Dang, Weiwei; Berger, Shelley L; Villanueva, Jessie; Meggers, Eric; Marmorstein, Ronen
2015 JMC Volume 58 Issue 1 January (16).pdf.jpg2015Comprehensive Analysis of Three-Dimensional Activity Cli ff s Formed by Kinase Inhibitors with Di ff erent Binding Modes and Cli ff Mapping of Structural AnaloguesFurtmann, Norbert; Hu, Ye
2015 JMC Volume 58 Issue 1 January (3).pdf.jpg2015Current Compound Coverage of the KinomeHu, Ye; Furtmann, Norbert
2015 JMC Volume 58 Issue 10 May (15).pdf.jpg2015Rational design of dual peptides targeting ghrelin and Y<inf>2</inf> receptors to regulate food intake and body weightKilian, Tom Marten; Klöting, Nora; Bergmann, Ralf; Els-Heindl, Sylvia; Babilon, Stefanie; Clément-Ziza, Mathieu; Zhang, Yixin; Beck-Sickinger, Annette G.; Chollet, Constance
2015 JMC Volume 58 Issue 1 January (8).pdf.jpg2015Campbell Family Institute for Breast Cancer Research, TMDT East Tower, MaRS Centre, 101 College Street, Toronto, Ontario MG5 1L7, Canada ‡ Princess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 2C4, CanadaSampson, Peter B; Liu, Yong; Patel, Narendra Kumar; Feher, Miklos; Forrest, Bryan; Li, Sze-wan; Edwards, Louise; Laufer, Radoslaw; Lang, Yunhui; Ban, Fuqiang; Awrey, Donald E; Mao, Guodong; Plotnikova, Olga; Leung, Genie; Hodgson, Richard; Mason, Jacqueline; Wei, Xin; Kia
2015 JMC Volume 58 Issue 1 January (27).pdf.jpg2015Jaclyn L. Henderson, † Bethany L. Kormos, † Matthew M. Hayward, ∥ Karen J. Co ff man, ∥ Jayasankar Jasti, ∥ Ravi G. Kurumbail, ∥ Travis T. Wager, † Patrick R. Verhoest, † G. Stephen Noell, ⊥ Yi Chen, ‡ Elie Needle, ‡ Zdenek Berger, ‡ Stefanus J. Steyn, §Henderson, Jaclyn L; Kormos, Bethany L; Hayward, Matthew M; Co, Karen J; Jasti, Jayasankar; Kurumbail, Ravi G; Wager, Travis T; Verhoest, Patrick R; Noell, G Stephen; Chen, Yi; Needle, Elie; Berger, Zdenek; Steyn, Stefanus J; Houle, Christopher; Hirst, Warren D; Galatsi
2015 JMC Volume 58 Issue 1 January (17).pdf.jpg2015Converting Potent Indeno[1,2 ‑ b ]indole Inhibitors of Protein Kinase CK2 into Selective Inhibitors of the Breast Cancer Resistance Protein ABCG2Gozzi, Gustavo Jabor; Bouaziz, Zouhair; Winter, Evelyn; Da, Nathalia; Aichele, Dagmar; Nacereddine, Abdelhamid; Marminon, Christelle; Valdameri, Glaucio; Bollacke, Andre; Guillon, Jean; Lacoudre, Aline; Cadena, Silvia M; Jose, Joachim; Borgne, Marc Le; Pietro, Attilio
2015 JMC Volume 58 Issue 1 January (21).pdf.jpg2015Exploring the Sca ff old Universe of Kinase InhibitorsHu, Ye

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