صفحه اصلی مجموعه  Journal of Medicinal Chemistry

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130.pdf.jpg24-Jun-2014The Discovery of Polo-Like Kinase 4 Inhibitors: Design and Optimization of Spiro[cyclopropane-1,3'[3H]indol]-2'(1'H)-ones as Orally Bioavailable Antitumor AgentsSampson, Peter B; Liu, Yong; Patel, Narendra Kumar; Feher, Miklos; Forrest, Bryan; Li, Sze-Wan; Edwards, Louise; Laufer, Radoslaw; Lang, Yunhui; Ban, Fuqiang; Awrey, Donald E; Mao, Guodong; Plotnikova, Olga; Leung, Genie; Hodgson, Richard; Mason, Jacqueline; Wei, Xin; Kiarash, Reza; Green, Erin; Qiu, Wei; Chirgadze, Nickolay Y; Mak, Tak W; Pan, Guohua; Pauls, Henry W
2015 JMC Volume 58 Issue 18 September (28).pdf.jpg2015Benzimidazole Derivatives as Potent JAK1-Selective InhibitorsKim, Mi Kyoung; Shin, Heerim; Park, Kwang Su; Kim, Hyungmi; Park, Jiseon; Kim, Kangjeon; Nam, Joonwoo; Choo, Hyunah; Chong, Youhoon
2015 JMC Volume 58 Issue 18 September (23).pdf.jpg2015Structure-Activity Relationship Studies of Orally Active Antimalarial 2,4-Diamino-thienopyrimidinesGonz??lez Cabrera, Diego; Douelle, Frederic; Le Manach, Claire; Han, Ze; Paquet, Tanya; Taylor, Dale; Njoroge, Mathew; Lawrence, Nina; Wiesner, Lubbe; Waterson, David; Witty, Michael J.; Wittlin, Sergio; Street, Leslie J.; Chibale, Kelly
2015 JMC Volume 58 Issue 18 September (2).pdf.jpg2015Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune DiseasesFarmer, Luc J.; Ledeboer, Mark W.; Hoock, Thomas; Arnost, Michael J.; Bethiel, Randy S.; Bennani, Youssef L.; Black, James J.; Brummel, Christopher L.; Chakilam, Ananthsrinivas; Dorsch, Warren A.; Fan, Bin; Cochran, John E.; Halas, Summer; Harrington, Edmund M.; Hogan,
2015 JMC Volume 58 Issue 18 September (6).pdf.jpg20156-Hydroxy-1,2,4-triazine-3,5(2 <i>H</i> ,4 <i>H</i> )-dione Derivatives as Novel <scp>d</scp> -Amino Acid Oxidase InhibitorsHin, Niyada; Duvall, Bridget; Ferraris, Dana; Alt, Jesse; Thomas, Ajit G.; Rais, Rana; Rojas, Camilo; Wu, Ying; Wozniak, Krystyna M.; Slusher, Barbara S.; Tsukamoto, Takashi
2015 JMC Volume 58 Issue 18 September (24).pdf.jpg2015Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [45Ti](salan)Ti(dipic)Severin, Gregory W.; Nielsen, Carsten H.; Jensen, Andreas I.; Fonslet, Jesper; Kj??r, Andreas; Zhuravlev, Fedor
2015 JMC Volume 58 Issue 18 September (27).pdf.jpg2015Inhibitors of BCATm: A Tough Nut To CrackScanlon, Martin
2015 JMC Volume 58 Issue 19 October (7).pdf.jpg2015Hirsutinolide Series Inhibit Stat3 Activity, Alter GCN1, MAP1B, Hsp105, G6PD, Vimentin, TrxR1, and Importin α-2 Expression, and Induce Antitumor Effects against Human GliomaMiklossy, Gabriella; Youn, Ui Joung; Yue, Peibin; Zhang, Mingming; Chen, Chih Hong; Hilliard, Tyvette S.; Paladino, David; Li, Yifei; Choi, Justin; Sarkaria, Jann N.; Kawakami, Joel K.; Wongwiwatthananukit, Supakit; Chen, Yuan; Sun, Dianqing; Chang, Leng Chee; Turkson,
2015 JMC Volume 58 Issue 19 October (3).pdf.jpg2015Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors of Trypanosoma bruceiCleghorn, Laura A T; Albrecht, S??bastien; Stojanovski, Laste; Simeons, Frederick R J; Norval, Suzanne; Kime, Robert; Collie, Iain T.; De Rycker, Manu; Campbell, Lorna; Hallyburton, Irene; Frearson, Julie A.; Wyatt, Paul G.; Read, Kevin D.; Gilbert, Ian H.
2015 JMC Volume 58 Issue 19 October (4).pdf.jpg2015Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer TargetWatson, Gabrielle M.; Gunzburg, Menachem J.; Ambaye, Nigus D.; Lucas, William A H; Traore, Daouda A.; Kulkarni, Ketav; Cergol, Katie M.; Payne, Richard J.; Panjikar, Santosh; Pero, Stephanie C.; Perlmutter, Patrick; Wilce, Matthew C J; Wilce, Jacqueline A.
2015 JMC Volume 58 Issue 19 October (9).pdf.jpg2015Structure-Affinity Relationship Analysis of Selective FKBP51 LigandsFeng, Xixi; Sippel, Claudia; Bracher, Andreas; Hausch, Felix
2015 JMC Volume 58 Issue 19 October (6).pdf.jpg2015Enhancement of Selectivity of an Organometallic Anticancer Agent by Redox ModulationRomero-Canel??n, Isolda; Mos, Magdalena; Sadler, Peter J.
2015 JMC Volume 58 Issue 19 October (8).pdf.jpg2015Design, Synthesis, and Biological Activity of Sulfonamide Analogues of Antofine and Cryptopleurine as Potent and Orally Active Antitumor AgentsKwon, Yongseok; Song, Jayoung; Lee, Honggu; Kim, Eun Yeong; Lee, Kiho; Lee, Sang Kook; Kim, Sanghee
2015 JMC Volume 58 Issue 19 October (5).pdf.jpg2015Phenylalanine and Phenylglycine Analogues as Arginine Mimetics in Dengue Protease InhibitorsWeigel, Lena F.; Nitsche, Christoph; Graf, Dominik; Bartenschlager, Ralf; Klein, Christian D.
2015 JMC Volume 58 Issue 2 January (10).pdf.jpg2015Synthesis and Carbonic Anhydrase Isoenzymes I, II, IX, and XII Inhibitory E ff ects of Dimethoxybromophenol Derivatives Incorporating Cyclopropane MoietiesBoztas, Murat; Topal, Meryem; Menzek, Abdullah; Tanc, Muhammet; Supuran, Claudiu T
2015 JMC Volume 58 Issue 2 January (1).pdf.jpg2015Epigenetics: Novel Therapeutics Targeting EpigeneticsTherapeutics, Novel; Epigenetics, Targeting
2015 JMC Volume 58 Issue 2 January (11).pdf.jpg2015Design, Synthesis, Biochemical, and Antiviral Evaluations of C6 Benzyl and C6 Biarylmethyl Substituted 2 ‑ Hydroxylisoquinoline-1,3- diones: Dual Inhibition against HIV Reverse Transcriptase-Associated RNase H and Polymerase with Antiviral ActivitiesVernekar, Sanjeev Kumar V; Liu, Zheng; Nagy, Eva; Miller, Lena; Kirby, Karen A; Wilson, Daniel J; Kankanala, Jayakanth; Sara, Stefan G; Parniak, Michael A; Wang, Zhengqiang
2015 JMC Volume 58 Issue 2 January (31).pdf.jpg2015Novel Tetrahydropyran-Based Bacterial Topoisomerase Inhibitors with Potent Anti-Gram Positive Activity and Improved Safety Pro fi leSurivet, Jean-philippe; Zumbrunn, Cornelia; Rueedi, Georg; Bur, Daniel; Bruye, Thierry; Locher, Hans; Ritz, Daniel; Seiler, Peter; Kohl, Christopher; Ertel, Eric A; Hess, Patrick; Gauvin, Jean-christophe; Mirre, Azely; Kaegi, Verena; Santos, Marina Dos; Gaertner, Mika; D
2015 JMC Volume 58 Issue 2 January (25).pdf.jpg2015Novel Antitumor Cisplatin and Transplatin Derivatives Containing 1 ‑ Methyl-7-Azaindole: Synthesis, Characterization, and Cellular ResponsesPracharova, Jitka; Saltarella, Teresa; Muchova, Tereza Radosova; Scintilla, Simone; Novohradsky, Vojtech; Novakova, Olga; Intini, Francesco P; Paci, Concetta; Natile, Giovanni; Ilik, Petr; Brabec, Viktor; Kasparkova, Jana
2015 JMC Volume 58 Issue 2 January (2).pdf.jpg2015Recent Advances in the Development of Acetyl-CoA Carboxylase (ACC) Inhibitors for the Treatment of Metabolic DiseaseBourbeau, Matthew P; Bartberger, Michael D