صفحه اصلی مجموعه  Journal of Medicinal Chemistry

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130.pdf.jpg24-Jun-2014The Discovery of Polo-Like Kinase 4 Inhibitors: Design and Optimization of Spiro[cyclopropane-1,3'[3H]indol]-2'(1'H)-ones as Orally Bioavailable Antitumor AgentsSampson, Peter B; Liu, Yong; Patel, Narendra Kumar; Feher, Miklos; Forrest, Bryan; Li, Sze-Wan; Edwards, Louise; Laufer, Radoslaw; Lang, Yunhui; Ban, Fuqiang; Awrey, Donald E; Mao, Guodong; Plotnikova, Olga; Leung, Genie; Hodgson, Richard; Mason, Jacqueline; Wei, Xin; Kiarash, Reza; Green, Erin; Qiu, Wei; Chirgadze, Nickolay Y; Mak, Tak W; Pan, Guohua; Pauls, Henry W
2016 JMC Volume 59 Issue 1 January (28).pdf.jpg2016Phenyl Benzenesulfonylhydrazides Exhibit Selective Indoleamine 2,3-Dioxygenase Inhibition with Potent in Vivo Pharmacodynamic Activity and Antitumor E ffi cacyLin, Shu-yu; Yeh, Teng-kuang; Kuo, Ching-chuan; Song, Jen-shin; Cheng, Ming-fu; Liao, Fang-yu; Chao, Min-wu; Huang, Han-li; Chen, Yi-lin; Yang, Chun-yu; Wu, Mine-hsine; Hsieh, Chia-ling; Hsiao, Wenchi; Peng, Yi-hui; Wu, Jian-sung; Lin, Li-mei; Sun, Manwu; Chao, Yu-sheng
2016 JMC Volume 59 Issue 1 January (29).pdf.jpg2016Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3K δ InhibitorsShin, Youngsook; Suchomel, Julia; Cardozo, Mario; Duquette, Jason; He, Xiao; Henne, Kirk; Hu, Yi-ling; Kelly, Ron C; Mccarter, John; Mcgee, Lawrence R; Medina, Julio C; Metz, Daniela; Miguel, Tisha San; Mohn, Deanna; Tran, Thuy; Vissinga, Christine; Wong, Simon; Wannberg,
2016 JMC Volume 59 Issue 1 January (35).pdf.jpg2016Correction to Discovery of 2 ‑ Pyridinone Aminals : A Prodrug Strategy to Advance a Second Generation of HIV ‑ 1 Integrase Strand Transfer InhibitorsRaheem, Izzat T; Walji, Abbas M; Klein, Daniel; Sanders, John M; Powell, David A; Abeywickrema, Pravien; Barbe, Guillaume; Bennet, Amrith; Childers, Karla; Christensen, Melodie; Clas, Sophie Dorothee; Dubost, David; Embrey, Mark; Grobler, Jay; Hafey, Michael J; Hartingh
2016 JMC Volume 59 Issue 1 January (30).pdf.jpg2016Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Di ff erent Binding Modes at AMPA ReceptorsSzymanska, Ewa; Frydenvang, Karla; Pickering, Darryl S; Krintel, Christian; Nielsen, Birgitte; Kooshki, Ayesheh; Zachariassen, Linda G; Olsen, Lars; Kastrup, Jette S; Johansen, Tommy N
2016 JMC Volume 59 Issue 1 January (31).pdf.jpg2016Synthesis of Triphenylethylene Bisphenols as Aromatase Inhibitors That Also Modulate Estrogen ReceptorsLv, Wei; Liu, Jinzhong; Skaar, Todd C; Neill, Elizaveta O; Yu, Ge; Flockhart, David A; Cushman, Mark
2016 JMC Volume 59 Issue 1 January (3).pdf.jpg2016Structural Insights into the Competitive Binding of Diclofenac and Naproxen by Equine Serum AlbuminSekula, Bartosz; Bujacz, Anna
2016 JMC Volume 59 Issue 1 January (32).pdf.jpg2016Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to CoumarinsFlorence, Sesto Fiorentino
2016 JMC Volume 59 Issue 1 January (33).pdf.jpg2016Allosteric Modulators: A Side DoorAbood, Mary E
2016 JMC Volume 59 Issue 1 January (34).pdf.jpg2016Computational Methods for Drug Discovery and Design-
2016 JMC Volume 59 Issue 3 February (32).pdf.jpg2016Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic AcidVu, Chi B; Bemis, Jean E; Benson, Ericka; Bista, Pradeep; Carney, David; Fahrner, Richard; Lee, Diana; Liu, Feng; Lonkar, Pallavi; Milne, Jill C; Nichols, Andrew J; Picarella, Dominic; Shoelson, Adam; Smith, Jesse; Ting, Amal; Wensley, Allison; Yeager, Maisy; Zimmer, Mich
2016 JMC Volume 59 Issue 3 February (27).pdf.jpg2016Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment InhibitorFreitas, Renato Ferreira De; Eram, Mohammad S; Szewczyk, Magdalena M; Steuber, Holger; Smil, David; Wu, Hong; Li, Fengling; Senisterra, Guillermo; Dong, Aiping; Brown, Peter J; Hitchcock, Marion; Moosmayer, Dieter; Stegmann, Christian M; Egner, Ursula; Arrowsmith, Cher
2016 JMC Volume 59 Issue 3 February (28).pdf.jpg2016Structure − Activity Relationship Study of Rakicidins: Overcoming Chronic Myeloid Leukemia Resistance to Imatinib with 4 ‑ Methylester-Rakicidin ASang, Feng; Ding, Yahui; Wang, Jinghan; Sun, Bingxia; Sun, Jianlei; Geng, Yan; Zhang, Zhang; Ding, Ke; Wu, Ling-ling; Liu, Jian-wei; Bai, Cuigai; Yang, Guang; Zhang, Quan; Li, Lu-yuan; Chen, Yue
2016 JMC Volume 59 Issue 3 February (30).pdf.jpg2016Potent μ ‑ Opioid Receptor Agonists from Cyclic Peptides Tyr ‑ c [Li, Yangmei; Cazares, Margret; Wu, Jinhua; Houghten, Richard A; Toll, Laurence; Dooley, Colette; Pines, Torrey; Studies, Molecular; Parkway, S W Village; Lucie, Port St
2016 JMC Volume 59 Issue 3 February (34).pdf.jpg2016Correction to Phenyl Ether- and Aniline-Containing 2 ‑ Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide SynthaseCinelli, Maris A; Li, Huiying; Pensa, Anthony V; Kang, Soosung; Roman, Linda J; Marta, Pavel
2016 JMC Volume 59 Issue 3 February (33).pdf.jpg2016Correction to Phenyl Ether- and Aniline-Containing 2 ‑ Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide SynthaseCinelli, Maris A; Li, Huiying; Pensa, Anthony V; Kang, Soosung; Roman, Linda J; Marta, Pavel
2016 JMC Volume 59 Issue 3 February (29).pdf.jpg2016Novel Water-Soluble Amphotericin B ‑ PEG Conjugates with Low Toxicity and Potent in Vivo E ffi cacyHalperin, Assaf; Shadkchan, Yana; Pisarevsky, Evgeni; Szpilman, Alex M; Sandovsky, Hani; Osherov, Nir; Benhar, Itai
2016 JMC Volume 59 Issue 3 February (31).pdf.jpg2016Discovery of Highly Potent Inhibitors Targeting the Predominant Drug-Resistant S31N Mutant of the In fl uenza A Virus M2 Proton ChannelLi, Fang; Degrado, William F; Wang, Jun
2016 JMC Volume 59 Issue 3 February (3).pdf.jpg2016Discovery of Molecular Therapeutics for Glaucoma: Challenges, Successes, and Promising DirectionsDonegan, Rebecca K; Lieberman, Raquel L
2016 JMC Volume 59 Issue 5 March (19).pdf.jpg2016Mimicking of Arginine by Functionalized N ω ‑ Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides : High A ffi nity Angiotensin , Neuropeptide Y , Neuropeptide FF , and Neurotensin Receptor Ligands As ExamplesKeller, Max; Kuhn, Kilian K; Einsiedel, Ju; Hu, Harald; Biselli, Sabrina; Mollereau, Catherine; Wi, David; Svobodova, Jaroslava; Bernhardt, Gu; Cabrele, Chiara; Vanderheyden, Patrick M L; Gmeiner, Peter; Buschauer, Armin

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